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Dr Natalie Boonzaier Research Associate Home Page: https://iris.ucl.ac.uk/iris/browse/profile?upi=NRBOO76 Email: nats.boonzaier@gmail.com
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My primary interests involve utilising multimodal MRI methods to better understand the biology of brain tumours and their microenvironment.
Past research projects have involved combining diffusion tensor imaging, perfusion-weighted imaging and MR-spectroscopy to identify regions of interest that may be responsible for treatment failure of glioblastoma. My current research is focused on using DTI tractography and arterial spin labelling to identify imaging features associated with loss of visual function in children with optic pathway gliomas.
Background
| 2017- present |
Research Associate – MR Image Analyst Developmental Imaging and Biophysics Section, UCL Great Ormond Street Institute of Child Health. |
| 2012 – 2016 |
PhD (University of Cambridge) – Clinical Neurosciences Multimodal MRI analysis of contrast-enhancing and non-enhancing components of glioblastoma. |
Selected Publications
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van Dijken B.R., Yan J.L., Boonzaier N.R., Li C., van Laar P.J., van der Hoorn A., Price S.J. (2017) “Subventricular zone involvement characterised by DTI in Glioblastoma” World Neurosurgery. (in press) doi: 10.1016/j.wneu.2017.06.075.
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Boonzaier N.R., Larkin T.J., Matys T., van der Hoorn A., Yan J.L., Price S.J. (2016) “Prognostic value of multiparametric assessment of diffusion and perfusion in contrast-enhancing and non-enhancing components in glioblastoma” Radiology (in press).
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Van der Hoorn A., Yan J.L., Larkin T.J., Boonzaier N.R., Matys T., Price S.J. (2016) “Posttreatment apparent diffusion coefficient changes in the periresectional area in patients with glioblastoma” World Neurosurgery 92:159-165. doi: http://dx.doi.org/10.1016/j.wneu.2016.04.129.
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Van der Hoorn A., Yan J.L., Larkin T.J., Boonzaier N.R., Matys T., Price S.J. (2016) “Validation of a semi-automatic co-registration of MRI scans in patients with brain tumors during treatment follow-up” NMR Biomedicine 29(7):882-889. doi: 10.1002/nbm.3538.
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Price S.J., Allinson K., Liu H., Boonzaier N.R., Yan J.L., Lupson V.C., Larkin T.J. (2016) “IDH-1 mutated glioblastomas have a less invasive phenotype than IDH-1 wild type glioblastomas: a diffusion tensor imaging study” Radiology (in press).
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Narayanana P.L., Warton C., Boonzaier N.R., Molteno C.D., Joseph J., Jacobson J.L., Jacobson S.W., Zöllei L., Meintjes E.M. (2016) “Improved segmentation of cerebellar structures in children” Journal of Neuroscience Methods 262:1-13. doi: 10.1016/j.jneumeth.2015.12.010.
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Yan J.L., van der Hoorn A., Larkin T.J., Boonzaier N.R., Matys T., Price S.J. (2016) “Extent of resection of peritumoural DTI abnormality as a predictor of survival in adult glioblastoma patients” Journal of Neurosurgery Published Online April 8; doi: 10.3171/2016.1.JNS152153.
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Boonzaier N.R., Piccirillo S.G.M., Watts C., Price S.J. (2015) “Assessing and monitoring intratumor heterogeneity in glioblastoma: how far has multimodal imaging come?” CNS Oncology 4(6):399-410. doi:10.2217/cns.15.20.
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Price S.J., Young A.M.H., Scotton W.J., Ching J., Mohsen L.A., Boonzaier N.R., Lupson V.C., Griffiths J.R., McLean M.A., Larkin T.J. (2015) “Multimodal MRI can identify perfusion and metabolic changes in the invasive margin of glioblastoms” Journal of Magnetic Resonance Imaging 43(2):487-494. doi: 10.1002/jmri.24996
